Grant TypePost PhD Research Grant
Institutional AffiliationMassachusetts, Amherst, U. of
Grant numberGr. 9394
Approve DateApril 18, 2017
Project TitleBabbitt, Dr. Courtney C., U. of Massachusetts, Amherst, MA - To aid research on 'Genomic Adaptation and the Evolution of Human Neural Phenotypes'
Preliminary abstract: This proposal seeks to investigate the links between signatures of adaptation (positive natural selection) at the level of regulatory DNA and how those sequence changes impact an organism’s phenotype. This proposal uses comparisons of humans with non-human primates to better understand the role natural selection has played in the evolution of neural gene expression in the hominin lineage. This study will be performed using a combination of next-generation sequencing and in vitro assays of gene expression in primate induced pluripotent stem cells (iPSCs).